Cefalonium
Chemical compound
- QJ51DB90 (WHO)
- Veterinary use only
- (6R,7R)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- 5575-21-3
- 21743
- 20438
- K2P920217W
- D07634
- ChEMBL2105567
- DTXSID5045388
- Interactive image
- O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)Cc3sccc3)C[n+]4ccc(C(=O)N)cc4)C([O-])=O
Cefalonium (INN) is a first-generation cephalosporin antibiotic.[1]
References
- ^ Boothe DN (2008). "Principles of Antibacterial Therapy". In Maddison JE, Page SW, Church DB (eds.). Small animal clinical pharmacology (Second ed.). [Edinburgh]: Elsevier Health Sciences. p. 167. ISBN 978-0-7020-2858-8.
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(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases)
Glycopeptides Lipoglycopeptides |
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Lipopeptides |
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Polymyxins |
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Other |
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- Inhibit PG subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
- Hydrolyze NAM-NAG
- Tyrothricin
- Isoniazid#
- Teixobactin
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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