CXCL6 |
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Identifiers |
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Aliases | CXCL6, CKA-3, GCP-2, GCP2, SCYB6, C-X-C motif chemokine ligand 6 |
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External IDs | OMIM: 138965; MGI: 1096868; HomoloGene: 88671; GeneCards: CXCL6; OMA:CXCL6 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 4 (human)[1] |
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| Band | 4q13.3 | Start | 73,836,640 bp[1] |
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End | 73,849,064 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 5 (mouse)[2] |
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| Band | 5 E1|5 44.78 cM | Start | 90,907,219 bp[2] |
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End | 90,909,483 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - bronchial epithelial cell
- palpebral conjunctiva
- spleen
- olfactory zone of nasal mucosa
- cartilage tissue
- islet of Langerhans
- beta cell
- parietal pleura
- jejunal mucosa
- sperm
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| Top expressed in | - right lobe of liver
- cervix
- endothelial cell of lymphatic vessel
- trachea
- respiratory epithelium
- olfactory epithelium
- mandibular molars
- embryo
- embryo
- conjunctival fornix
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - cytokine activity
- CXCR chemokine receptor binding
- heparin binding
- chemokine activity
- protein binding
| Cellular component | - extracellular region
- extracellular space
| Biological process | - chemotaxis
- cell-cell signaling
- chemokine-mediated signaling pathway
- regulation of cell population proliferation
- defense response to bacterium
- signal transduction
- neutrophil mediated immunity
- defense response
- positive regulation of neutrophil chemotaxis
- neutrophil chemotaxis
- neutrophil activation
- antimicrobial humoral immune response mediated by antimicrobial peptide
- cellular response to lipopolysaccharide
- inflammatory response
- immune response
- regulation of signaling receptor activity
- G protein-coupled receptor signaling pathway
- leukocyte homeostasis
- leukocyte chemotaxis
- response to lipopolysaccharide
- regulation of chemokine production
- regulation of neutrophil mediated killing of gram-negative bacterium
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 4: 73.84 – 73.85 Mb | Chr 5: 90.91 – 90.91 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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